Translational regulation shapes the molecular landscape of complex disease phenotypes

The extent of translational control of gene expression in mammalian tissues remains largely unknown. Here we perform genome-wide RNA sequencing and ribosome profiling in heart and liver tissues to investigate strain-specific translational regulation in the spontaneously hypertensive rat (SHR/Ola). F...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Schafer, Sebastian, Adami, Eleonora, Heinig, Matthias, Rodrigues, Katharina E. Costa, Kreuchwig, Franziska, Silhavy, Jan, van Heesch, Sebastiaan, Simaite, Deimante, Rajewsky, Nikolaus, Cuppen, Edwin, Pravenec, Michal, Vingron, Martin, Cook, Stuart A., Hubner, Norbert
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455061/
https://ncbi.nlm.nih.gov/pubmed/26007203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8200
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items