LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal

CONTEXT: Aldosterone synthesis and cellularity in the human adrenal zona glomerulosa (ZG) is sparse and patchy, presumably due to salt excess. The frequency of somatic mutations causing aldosterone-producing adenomas (APAs) may be a consequence of protection from cell loss by constitutive aldosteron...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Shaikh, Lalarukh Haris, Zhou, Junhua, Teo, Ada E. D., Garg, Sumedha, Neogi, Sudeshna Guha, Figg, Nichola, Yeo, Giles S., Yu, Haixiang, Maguire, Janet J., Zhao, Wanfeng, Bennett, Martin R., Azizan, Elena A. B., Davenport, Anthony P., McKenzie, Grahame, Brown, Morris J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Hot Topics in Translational Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454794/
https://ncbi.nlm.nih.gov/pubmed/25915569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-1734
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados