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Interleukin-10 paradox: A potent immunoregulatory cytokine that has been difficult to harness for immunotherapy

Interleukin-10 (IL-10) is arguably the most potent anti-inflammatory cytokine. It is produced by almost all the innate and adaptive immune cells. These cells also serve as its targets, indicating that IL-10 secretion and action is highly regulated and perhaps compartmentalized. Consistent with this...

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Detalhes bibliográficos
Publicado no:Cytokine
Main Authors: Saxena, Ankit, Khosraviani, Sam, Noel, Sanjeev, Mohan, Divya, Donner, Thomas, Hamad, Abdel Rahim A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454631/
https://ncbi.nlm.nih.gov/pubmed/25481648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2014.10.031
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