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The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult?

Axon regeneration in the CNS is inhibited by many extrinsic and intrinsic factors. Because these act in parallel, no single intervention has been sufficient to enable full regeneration of damaged axons in the adult mammalian CNS. In the external environment, NogoA and CSPGs are strongly inhibitory t...

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Détails bibliographiques
Publié dans:Neurochem Res
Auteur principal: Fawcett, James W.
Format: Artigo
Langue:Inglês
Publié: Springer US 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942574/
https://ncbi.nlm.nih.gov/pubmed/31388931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-019-02844-y
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