Nrf2 activation protects against solar-simulated ultraviolet radiation in mice and humans

The transcription factor Nrf2 determines the ability to adapt and survive under conditions of electrophilic, oxidative and inflammatory stress by regulating the expression of elaborate networks comprising nearly 500 genes encoding proteins with versatile cytoprotective functions. In mice, disruption...

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Udgivet i:Cancer Prev Res (Phila)
Main Authors: Knatko, Elena V., Ibbotson, Sally H., Zhang, Ying, Higgins, Maureen, Fahey, Jed W., Talalay, Paul, Dawe, Robert S., Ferguson, James, Huang, Jeffrey T.-J., Clarke, Rosemary, Zheng, Suqing, Saito, Akira, Kalra, Sukirti, Benedict, Andrea L., Honda, Tadashi, Proby, Charlotte M., Dinkova-Kostova, Albena T.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454593/
https://ncbi.nlm.nih.gov/pubmed/25804610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0362
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