The RING ubiquitin E3 RNF114 interacts with A20 and modulates NF-κB activity and T-cell activation

Accurate regulation of nuclear factor-κB (NF-κB) activity is crucial to prevent a variety of disorders including immune and inflammatory diseases. Active NF-κB promotes IκBα and A20 expression, important negative regulatory molecules that control the NF-κB response. In this study, using two-hybrid s...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Rodriguez, M S, Egaña, I, Lopitz-Otsoa, F, Aillet, F, Lopez-Mato, M P, Dorronroso, A, Lobato-Gil, S, Sutherland, J D, Barrio, R, Trigueros, C, Lang, V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454333/
https://ncbi.nlm.nih.gov/pubmed/25165885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.366
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