Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ

Targeting the actin cytoskeleton (CSK) of cancer cells offers a valuable strategy in cancer therapy. There are a number of natural compounds that interfere with the actin CSK, but the mode of their cytotoxic action and, moreover, their tumor-specific mechanisms are quite elusive. We used the myxobac...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Foerster, F, Braig, S, Moser, C, Kubisch, R, Busse, J, Wagner, E, Schmoeckel, E, Mayr, D, Schmitt, S, Huettel, S, Zischka, H, Mueller, R, Vollmar, A M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454332/
https://ncbi.nlm.nih.gov/pubmed/25165884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.363
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