RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage

The receptor-interacting protein kinase 3 (RIP3) associates with RIP1 in a necrosome complex that can induce necroptosis, apoptosis, or cell proliferation. We analyzed the expression of RIP1 and RIP3 in CD34+ leukemia cells from a cohort of patients with acute myeloid leukemia (AML) and CD34+ cells...

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Publicat a:Cell Death Dis
Autors principals: Nugues, A-L, El Bouazzati, H, Hétuin, D, Berthon, C, Loyens, A, Bertrand, E, Jouy, N, Idziorek, T, Quesnel, B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454320/
https://ncbi.nlm.nih.gov/pubmed/25144719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.347
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