Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells

We examined the roles of Notch1 signaling and its cross-talk with other signaling pathways, including p53 and phosphatidylinositol-3-kinase (PI3K)/Akt, in cadmium-induced cellular damage in HK-2 human renal proximal tubular epithelial cells. Following exposure to cadmium chloride (CdCl(2)), the leve...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Fujiki, K, Inamura, H, Matsuoka, M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454314/
https://ncbi.nlm.nih.gov/pubmed/25118938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.339
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