Brimonidine reduces TGF-beta-induced extracellular matrix synthesis in human Tenon’s fibroblasts

BACKGROUND: Brimonidine is a highly selective α(2) adrenergic agonist that has been widely used in anti-glaucoma eyedrops. The aim of this study was to investigate its putative anti-fibrotic role in the fibrosis caused by activated Tenon’s fibroblasts. METHODS: Primary cultured human Tenon’s fibrobl...

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Vydáno v:BMC Ophthalmol
Hlavní autoři: Hong, Samin, Han, Sueng-Han, Kim, Chan Yun, Kim, Kang Yoon, Song, Yoo Kyung, Seong, Gong Je
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454273/
https://ncbi.nlm.nih.gov/pubmed/26017119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-015-0045-8
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