Itraconazole solid dispersion prepared by a supercritical fluid technique: preparation, in vitro characterization, and bioavailability in beagle dogs

This research aimed to develop a supercritical fluid (SCF) technique for preparing a particulate form of itraconazole (ITZ) with good dissolution and bioavailability characteristics. The ITZ particulate solid dispersion was formulated with hydroxypropyl methylcellulose, Pluronic F-127, and L-ascorbi...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Yin, Xuezhi, Daintree, Linda Sharon, Ding, Sheng, Ledger, Daniel Mark, Wang, Bing, Zhao, Wenwen, Qi, Jianping, Wu, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454206/
https://ncbi.nlm.nih.gov/pubmed/26060397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S81253
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