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An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions

Cell–cell adhesion couples the contractile cortices of epithelial cells together, generating tension to support a range of morphogenetic processes. E-cadherin adhesion plays an active role in generating junctional tension by promoting actin assembly and cortical signaling pathways that regulate myos...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Gomez, Guillermo A., McLachlan, Robert W., Wu, Selwin K., Caldwell, Benjamin J., Moussa, Elliott, Verma, Suzie, Bastiani, Michele, Priya, Rashmi, Parton, Robert G., Gaus, Katharina, Sap, Jan, Yap, Alpha S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454173/
https://ncbi.nlm.nih.gov/pubmed/25631816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-07-1223
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