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Dynamic instability 30 years later: complexities in microtubule growth and catastrophe

Microtubules are not like other polymers. Whereas polymers such as F-actin will grow continuously as long as the subunit concentration is high enough, a steadily growing microtubule can suddenly shrink even when there is ample αβ-tubulin around. This remarkable behavior was discovered in 1984 when T...

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Bibliographic Details
Published in:Mol Biol Cell
Main Author: Brouhard, Gary J.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454169/
https://ncbi.nlm.nih.gov/pubmed/25823928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-10-0594
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