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Redox control of glutamine utilization in cancer
Glutamine utilization promotes enhanced growth of cancer cells. We propose a new concept map of cancer metabolism in which mitochondrial NADH and NADPH, in the presence of a dysfunctional electron transfer chain, promote reductive carboxylation from glutamine. We also discuss why nicotinamide nucleo...
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| Udgivet i: | Cell Death Dis |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454159/ https://ncbi.nlm.nih.gov/pubmed/25476909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.513 |
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