Severe Myelotoxicity Associated with Thiopurine S-Methyltransferase*3A/*3C Polymorphisms in a Patient with Pediatric Leukemia and the Effect of Steroid Therapy

Myelosuppression is a serious complication during treatment of acute lymphoblastic leukemia and the duration of myelosuppression is affected by underlying bone marrow failure syndromes and drug pharmacogenetics caused by genetic polymorphisms. Mutations in the thiopurine S-methyltransferase (TPMT) g...

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Detaylı Bibliyografya
Yayımlandı:Turk J Haematol
Asıl Yazarlar: Belen, Burcu Fatma, Gürsel, Türkiz, Akyürek, Nalan, Albayrak, Meryem, Kaya, Zühre, Koçak, Ülker
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Galenos Publishing 2014
Konular:
Case Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454056/
https://ncbi.nlm.nih.gov/pubmed/25541649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.2013.0082
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