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Single-Molecule Imaging Reveals Dynamics of CREB Transcription Factor Bound to Its Target Sequence

Proper spatiotemporal gene expression is achieved by selective DNA binding of transcription factors in the genome. The most intriguing question is how dynamic interactions between transcription factors and their target sites contribute to gene regulation by recruiting the basal transcriptional machi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sugo, Noriyuki, Morimatsu, Masatoshi, Arai, Yoshiyuki, Kousoku, Yoshinori, Ohkuni, Aya, Nomura, Taishin, Yanagida, Toshio, Yamamoto, Nobuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454023/
https://ncbi.nlm.nih.gov/pubmed/26039515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10662
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