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Novel functions of chromatin-bound IκBα in oncogenic transformation

The nuclear factor-κB (NF-κB) signalling pathway participates in a multitude of biological processes, which imply the requirement of a complex and precise regulation. IκB (for Inhibitor of kappaB) proteins, which bind and retain NF-κB dimers in the cytoplasm, are the main contributors to negative re...

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Détails bibliographiques
Publié dans:Br J Cancer
Auteurs principaux: Espinosa, L, Bigas, A, Mulero, M C
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453743/
https://ncbi.nlm.nih.gov/pubmed/25233399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.84
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