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Association between KRAS mutation and lung metastasis in advanced colorectal cancer

BACKGROUND: KRAS mutations have been associated with lung metastases at diagnosis of metastatic colorectal cancer (mCRC), but the impact of this mutation on subsequent development of lung metastasis is unknown. We investigated KRAS mutation as a predictor of lung metastasis development. METHODS: We...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Pereira, A A L, Rego, J F M, Morris, V, Overman, M J, Eng, C, Garrett, C R, Boutin, A T, Ferrarotto, R, Lee, M, Jiang, Z-Q, Hoff, P M, Vauthey, J-N, Vilar, E, Maru, D, Kopetz, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453646/
https://ncbi.nlm.nih.gov/pubmed/25535726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.619
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