A Modified R-Type Bacteriocin Specifically Targeting Clostridium difficile Prevents Colonization of Mice without Affecting Gut Microbiota Diversity

Clostridium difficile is a leading cause of nosocomial infections worldwide and has become an urgent public health threat requiring immediate attention. Epidemic lineages of the BI/NAP1/027 strain type have emerged and spread through health care systems across the globe over the past decade. Limitin...

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Veröffentlicht in:mBio
Hauptverfasser: Gebhart, Dana, Lok, Stephen, Clare, Simon, Tomas, Myreen, Stares, Mark, Scholl, Dean, Donskey, Curtis J., Lawley, Trevor D., Govoni, Gregory R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Microbiology 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453579/
https://ncbi.nlm.nih.gov/pubmed/25805733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02368-14
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