Toxin Synthesis by Clostridium difficile Is Regulated through Quorum Signaling

Clostridium difficile infection (CDI) is dramatically increasing as a cause of antibiotic- and hospital-associated diarrhea worldwide. C. difficile, a multidrug-resistant pathogen, flourishes in the colon after the gut microbiota has been altered by antibiotic therapy. Consequently, it produces toxi...

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Bibliographic Details
Published in:mBio
Main Authors: Darkoh, Charles, DuPont, Herbert L., Norris, Steven J., Kaplan, Heidi B.
Format: Artigo
Language:Inglês
Published: American Society of Microbiology 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453554/
https://ncbi.nlm.nih.gov/pubmed/25714717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02569-14
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