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Bile Salt Inhibition of Host Cell Damage by Clostridium Difficile Toxins

Virulent Clostridium difficile strains produce toxin A and/or toxin B that are the etiological agents of diarrhea and pseudomembranous colitis. Treatment of C. difficile infections (CDI) has been hampered by resistance to multiple antibiotics, sporulation, emergence of strains with increased virulen...

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Detalhes bibliográficos
Main Authors: Darkoh, Charles, Brown, Eric L., Kaplan, Heidi B., DuPont, Herbert L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823588/
https://ncbi.nlm.nih.gov/pubmed/24244530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079631
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