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QTc interval prolongation with vascular endothelial growth factor receptor tyrosine kinase inhibitors

BACKGROUND: Multi-targeted vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKIs) are known to cause cardiac toxicity, but the relative risk (RR) of QTc interval prolongation and serious arrhythmias associated with them are not reported. METHODS: We conducted a trial-l...

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Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Ghatalia, P, Je, Y, Kaymakcalan, M D, Sonpavde, G, Choueiri, T K
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453446/
https://ncbi.nlm.nih.gov/pubmed/25349964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.564
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