Macrophage migration inhibitory factor confers resistance to senescence through CD74-dependent AMPK-FOXO3a signaling in mesenchymal stem cells

INTRODUCTION: Mesenchymal stem cells (MSCs)-based therapies have had positive outcomes in animal models of cardiovascular diseases. However, the number and function of MSCs decline with age, reducing their ability to contribute to endogenous injury repair. The potential of stem cells to restore dama...

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Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Xia, Wenzheng, Zhang, Fengyun, Xie, Congying, Jiang, Miaomiao, Hou, Meng
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453287/
https://ncbi.nlm.nih.gov/pubmed/25896286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0076-3
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