Celastrol ameliorates cytokine toxicity and pro-inflammatory immune responses by suppressing NF-κB activation in RINm5F beta cells

Upregulation of pro-inflammatory mediators contributes to β-cell destruction and enhanced infiltration of immune cells into pancreatic islets during development of type 1 diabetes mellitus. In this study, we examined the regulatory effects and the mechanisms of action of celastrol against cytotoxici...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMB Rep
Main Authors: Ju, Sung Mi, Youn, Gi Soo, Cho, Yoon Shin, Choi, Soo Young, Park, Jinseu
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research-Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453024/
https://ncbi.nlm.nih.gov/pubmed/25059279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2015.48.3.147
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados