Optimizing tumor targeting of the lipophilic EGFR-binding radiotracer SKI243 using a liposomal nanoparticle delivery system

Positron emission tomography (PET) of epidermal growth factor receptor (EGFR) kinase-specific radiolabeled tracers could provide a means for non-invasively characterizing EGFR expression and signaling activity in patients' tumors before, during, and after therapy with EGFR inhibitors. Towards t...

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Pubblicato in:J Control Release
Autori principali: Medina, Oula Penate, Pillarsetty, Nagavarakishore, Glekas, Athanasios, Punzalan, Blesida, Longo, Valerie, Gönen, Mithat, Zanzonico, Pat, Smith-Jones, Peter, Larson, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452957/
https://ncbi.nlm.nih.gov/pubmed/21047536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.10.024
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