Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype

The role of glutamate N-methyl-D-aspartate receptor (NMDAR) hypofunction has been extensively studied in schizophrenia; however, less is known about its role in anxiety disorders. Recently, it was demonstrated that astrocytic GLT-1 blockade leads to an anxiety-like phenotype. Although astrocytes are...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Neurosci
Prif Awduron: Zimmer, Eduardo R., Torrez, Vitor R., Kalinine, Eduardo, Augustin, Marina C., Zenki, Kamila C., Almeida, Roberto F., Hansel, Gisele, Muller, Alexandre P., Souza, Diogo O., Machado-Vieira, Rodrigo, Portela, Luis V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452887/
https://ncbi.nlm.nih.gov/pubmed/26089779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00219
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg