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Biliverdin reductase: a target for cancer therapy?
Biliverdin reductase (BVR) is a multifunctional protein that is the primary source of the potent antioxidant, bilirubin. BVR regulates activities/functions in the insulin/IGF-1/IRK/PI3K/MAPK pathways. Activation of certain kinases in these pathways is/are hallmark(s) of cancerous cells. The protein...
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| Pubblicato in: | Front Pharmacol |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4452799/ https://ncbi.nlm.nih.gov/pubmed/26089799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00119 |
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