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Biliverdin reductase: a target for cancer therapy?
Biliverdin reductase (BVR) is a multifunctional protein that is the primary source of the potent antioxidant, bilirubin. BVR regulates activities/functions in the insulin/IGF-1/IRK/PI3K/MAPK pathways. Activation of certain kinases in these pathways is/are hallmark(s) of cancerous cells. The protein...
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Udgivet i: | Front Pharmacol |
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Main Authors: | , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Frontiers Media S.A.
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4452799/ https://ncbi.nlm.nih.gov/pubmed/26089799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00119 |
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