Synthesis and preclinical evaluation of DOTAGA-conjugated PSMA ligands for functional imaging and endoradiotherapy of prostate cancer

BACKGROUND: Due to its high expression in prostate cancer, PSMA (prostate-specific membrane antigen) represents an ideal target for both diagnostic imaging and endoradiotherapeutic approaches. Based on a previously published highly specific PSMA ligand ([(68)Ga]DOTA-FFK(Sub-KuE)), we developed a cor...

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Bibliographic Details
Published in:EJNMMI Res
Main Authors: Weineisen, Martina, Simecek, Jakub, Schottelius, Margret, Schwaiger, Markus, Wester, Hans-Jürgen
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2014
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452638/
https://ncbi.nlm.nih.gov/pubmed/26116124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0063-1
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