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Trypanosoma brucei Bloodstream Forms Depend upon Uptake of myo-Inositol for Golgi Complex Phosphatidylinositol Synthesis and Normal Cell Growth

myo-Inositol is a building block for all inositol-containing phospholipids in eukaryotes. It can be synthesized de novo from glucose-6-phosphate in the cytosol and endoplasmic reticulum. Alternatively, it can be taken up from the environment via Na(+)- or H(+)-linked myo-inositol transporters. While...

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Pubblicato in:Eukaryot Cell
Autori principali: González-Salgado, Amaia, Steinmann, Michael, Major, Louise L., Sigel, Erwin, Reymond, Jean-Louis, Smith, Terry K., Bütikofer, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452569/
https://ncbi.nlm.nih.gov/pubmed/25888554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00038-15
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