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Transfer of Myelin-Reactive Th17 Cells Impairs Endogenous Remyelination in the Central Nervous System of Cuprizone-Fed Mice

Multiple sclerosis (MS) is a demyelinating disease of the CNS characterized by inflammation and neurodegeneration. Animal models that enable the study of remyelination in the context of ongoing inflammation are greatly needed for the development of novel therapies that target the pathological inhibi...

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Publicado no:J Neurosci
Main Authors: Baxi, Emily G., DeBruin, Joseph, Tosi, Dominique M., Grishkan, Inna V., Smith, Matthew D., Kirby, Leslie A., Strasburger, Hayley J., Fairchild, Amanda N., Calabresi, Peter A., Gocke, Anne R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452559/
https://ncbi.nlm.nih.gov/pubmed/26041928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3817-14.2015
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