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Contribution of Beta-HPV Infection and UV-Damage to Rapid-onset Cutaneous Squamous Cell Carcinoma during BRAF-inhibition Therapy

PURPOSE: BRAF-inhibition (BRAFi) therapy for advanced melanoma carries a high rate of secondary cutaneous squamous cell carcinoma (cSCC) and risk of other cancers. Ultraviolet (UV) radiation and α-genus human papillomavirus (HPV) are highly associated with SCC, but a novel role for β-genus HPV is su...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Cohen, Daniel N., Lawson, Steven K., Shaver, Aaron C., Du, Liping, Nguyen, Harrison P., He, Qin, Johnson, Douglas B., Lumbang, Wilfred A., Moody, Brent R., Prescott, James L., Chandra, Pranil K., Boyd, Alan S., Zwerner, Jeffrey P., Robbins, Jason B., Tyring, Stephen K., Rady, Peter L., Chappell, James D., Shyr, Yu, Infante, Jeffrey R., Sosman, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452444/
https://ncbi.nlm.nih.gov/pubmed/25724524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2667
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