Contribution of Beta-HPV Infection and UV-Damage to Rapid-onset Cutaneous Squamous Cell Carcinoma during BRAF-inhibition Therapy

PURPOSE: BRAF-inhibition (BRAFi) therapy for advanced melanoma carries a high rate of secondary cutaneous squamous cell carcinoma (cSCC) and risk of other cancers. Ultraviolet (UV) radiation and α-genus human papillomavirus (HPV) are highly associated with SCC, but a novel role for β-genus HPV is su...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Cohen, Daniel N., Lawson, Steven K., Shaver, Aaron C., Du, Liping, Nguyen, Harrison P., He, Qin, Johnson, Douglas B., Lumbang, Wilfred A., Moody, Brent R., Prescott, James L., Chandra, Pranil K., Boyd, Alan S., Zwerner, Jeffrey P., Robbins, Jason B., Tyring, Stephen K., Rady, Peter L., Chappell, James D., Shyr, Yu, Infante, Jeffrey R., Sosman, Jeffrey A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452444/
https://ncbi.nlm.nih.gov/pubmed/25724524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2667
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