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Molecular Pathways: Targeting Cellular Energy Metabolism in Cancer via Inhibition of SLC2A1 and LDHA

Reprogramming of cellular energy metabolism is widely accepted to be one of the main hallmarks of cancer. Aberrant expression pattern of key regulators in the glycolysis pathway in cancer cells corroborates with the hypothesis that most cancer cells utilize aerobic glycolysis as their main ATP produ...

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Bibliografiska uppgifter
I publikationen:Clin Cancer Res
Huvudupphovsmän: Ooi, Aik T., Gomperts, Brigitte N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452440/
https://ncbi.nlm.nih.gov/pubmed/25838393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1209
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