Anti-Inflammatory and Cytostatic Activities of a Parthenolide-Like Sesquiterpene Lactone from Cota palaestina subsp. syriaca

A sesquiterpene lactone 1-β,10-Epoxy-6-hydroxy-1,10H-inunolide (K100) was isolated through “bioassay-guided fractionation” from Cota palaestina subsp. syriaca, an Eastern Mediterranean endemic plant. K100 inhibited endotoxin- (ET-) induced proinflammatory markers: IL-6, MMP-9, and NO in normal mouse...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Talhouk, Rabih S., Nasr, Bilal, Fares, Mohamed-Bilal, Ajeeb, Bushra, Nahhas, Rana, Al Aaraj, Lamis, Talhouk, Salma N., Ghaddar, Tarek H., Saliba, Najat A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452324/
https://ncbi.nlm.nih.gov/pubmed/26089941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/474597
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