Loss of SOX9 Expression Is Associated with PSA Recurrence in ERG-Positive and PTEN Deleted Prostate Cancers

The transcription factor SOX9 plays a crucial role in normal prostate development and has been suggested to drive prostate carcinogenesis in concert with PTEN inactivation. To evaluate the clinical impact of SOX9 and its relationship with key genomic alterations in prostate cancer, SOX9 expression w...

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Udgivet i:PLoS One
Main Authors: Burdelski, Christoph, Bujupi, Erzen, Tsourlakis, Maria Christina, Hube-Magg, Claudia, Kluth, Martina, Melling, Nathaniel, Lebok, Patrick, Minner, Sarah, Koop, Christina, Graefen, Markus, Heinzer, Hans, Wittmer, Corinna, Sauter, Guido, Wilczak, Waldemar, Simon, Ronald, Schlomm, Thorsten, Steurer, Stefan, Krech, Till
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452277/
https://ncbi.nlm.nih.gov/pubmed/26030748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128525
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