The prognostic value of SUMO1/Sentrin specific peptidase 1 (SENP1) in prostate cancer is limited to ERG-fusion positive tumors lacking PTEN deletion

BACKGROUND: Posttranscriptional protein modification by SUMOylation plays an important role in tumor development and progression. In the current study we analyzed prevalence and prognostic impact of the de-SUMOylation enzyme SENP1 in prostate cancer. METHODS: SENP1 expression was analyzed by immunoh...

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Publicat a:BMC Cancer
Autors principals: Burdelski, Christoph, Menan, Devi, Tsourlakis, Maria Christina, Kluth, Martina, Hube-Magg, Claudia, Melling, Nathaniel, Minner, Sarah, Koop, Christina, Graefen, Markus, Heinzer, Hans, Wittmer, Corinna, Sauter, Guido, Simon, Ronald, Schlomm, Thorsten, Steurer, Stefan, Krech, Till
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512145/
https://ncbi.nlm.nih.gov/pubmed/26202067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1555-8
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