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Detailed Per-residue Energetic Analysis Explains the Driving Force for Microtubule Disassembly
Microtubules are long filamentous hollow cylinders whose surfaces form lattice structures of αβ-tubulin heterodimers. They perform multiple physiological roles in eukaryotic cells and are targets for therapeutic interventions. In our study, we carried out all-atom molecular dynamics simulations for...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4452272/ https://ncbi.nlm.nih.gov/pubmed/26030285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004313 |
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