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Analysis of the Strength of Interfacial Hydrogen Bonds between Tubulin Dimers Using Quantum Theory of Atoms in Molecules

Microtubules are key structural elements that, among numerous biological functions, maintain the cytoskeleton of the cell and have a major role in cell division, which makes them important cancer chemotherapy targets. Understanding the energy balance that brings tubulin dimers, the building blocks o...

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Detalhes bibliográficos
Main Authors: Ayoub, Ahmed T., Craddock, Travis J.A., Klobukowski, Mariusz, Tuszynski, Jack
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129478/
https://ncbi.nlm.nih.gov/pubmed/25099813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.05.047
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