Gab1 Is Modulated by Chronic Hypoxia in Children with Cyanotic Congenital Heart Defect and Its Overexpression Reduces Apoptosis in Rat Neonatal Cardiomyocytes

Gab1 (Grb2 associated binding protein 1) is a member of the scaffolding/docking proteins (Gab1, Gab2, and Gab3). It is required for fibroblast cell survival and maintaining cardiac function. Very little is known about human Gab1 expression in response to chronic hypoxia. The present study examined t...

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Pubblicato in:Biomed Res Int
Autori principali: Cherif, Myriam, Caputo, Massimo, Nakaoka, Yoshikazu, Angelini, Gianni D., Ghorbel, Mohamed T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452271/
https://ncbi.nlm.nih.gov/pubmed/26090437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/718492
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