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Transcriptomic analysis of patients with tetralogy of Fallot reveals the effect of chronic hypoxia on myocardial gene expression

OBJECTIVES: In cyanotic patients undergoing repair of heart defects, chronic hypoxia is thought to lead to greater susceptibility to ischemia and reoxygenation injury. We sought to find an explanation to such a hypothesis by investigating the cardiac gene expression in patients with tetralogy of Fal...

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Detalhes bibliográficos
Main Authors: Ghorbel, Mohamed T., Cherif, Myriam, Jenkins, Emma, Mokhtari, Amir, Kenny, Damien, Angelini, Gianni D., Caputo, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951593/
https://ncbi.nlm.nih.gov/pubmed/20416888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2009.12.055
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