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The Influence of Chitosan on the Oral Bioavailability of Acyclovir—a Comparative Bioavailability Study in Humans

PURPOSE: The effects of chitosan hydrochloride on the oral absorption of acyclovir in humans were studied to confirm the absorption enhancing effects reported for in vitro and rat studies, respectively. METHODS: A controlled, open-label, randomized, 3-phase study was conducted in 12 healthy human vo...

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Bibliographische Detailangaben
Veröffentlicht in:Pharm Res
Hauptverfasser: Kubbinga, Marlies, Nguyen, Mai Anh, Staubach, Petra, Teerenstra, Steven, Langguth, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452255/
https://ncbi.nlm.nih.gov/pubmed/25609011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1613-y
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