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Influence of a niosomal formulation on the oral bioavailability of acyclovir in rabbits

The purpose of this research was to prepare acyclovir niosomes in a trial to improve its poor and variable oral bioavailability. The nonionic surfactant vesicles were prepared by the conventional thin film hydration method. The lipid mixture consisted of cholesterol, span 60, and dicetyl phosphate i...

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Autors principals: Attia, Ismail A., El-Gizawy, Sanaa A., Fouda, Medhat A., Donia, Ahmed M.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750692/
https://ncbi.nlm.nih.gov/pubmed/18181527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0804106
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