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Epidermal growth factor receptor and AKT1 gene copy numbers by multi-gene fluorescence in situ hybridization impact on prognosis in breast cancer

The epidermal growth factor receptor (EGFR)/PI3K/AKT signaling pathway aberrations play significant roles in breast cancer occurrence and development. However, the status of EGFR and AKT1 gene copy numbers remains unclear. In this study, we showed that the rates of EGFR and AKT1 gene copy number alt...

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Li, Jiao, Su, Wei, Zhang, Sheng, Hu, Yunhui, Liu, Jingjing, Zhang, Xiaobei, Bai, Jingchao, Yuan, Weiping, Hu, Linping, Cheng, Tao, Zetterberg, Anders, Lei, Zhenmin, Zhang, Jin
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452167/
https://ncbi.nlm.nih.gov/pubmed/25702787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12637
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