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Epidermal growth factor receptor and AKT1 gene copy numbers by multi-gene fluorescence in situ hybridization impact on prognosis in breast cancer

The epidermal growth factor receptor (EGFR)/PI3K/AKT signaling pathway aberrations play significant roles in breast cancer occurrence and development. However, the status of EGFR and AKT1 gene copy numbers remains unclear. In this study, we showed that the rates of EGFR and AKT1 gene copy number alt...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Sci
Hauptverfasser: Li, Jiao, Su, Wei, Zhang, Sheng, Hu, Yunhui, Liu, Jingjing, Zhang, Xiaobei, Bai, Jingchao, Yuan, Weiping, Hu, Linping, Cheng, Tao, Zetterberg, Anders, Lei, Zhenmin, Zhang, Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452167/
https://ncbi.nlm.nih.gov/pubmed/25702787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12637
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