BRCA/Fanconi anemia pathway implicates chemoresistance to gemcitabine in biliary tract cancer

The BRCA/Fanconi anemia (FA) pathway plays a key role in the repair of DNA double strand breaks. We focused on this pathway to clarify chemoresistance mechanisms in biliary tract cancer (BTC). We also investigated changes in the CD24(+)/44(+) population that may be involved in chemoresistance, as th...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Nakashima, Shinsuke, Kobayashi, Shogo, Nagano, Hiroaki, Tomokuni, Akira, Tomimaru, Yoshito, Asaoka, Tadafumi, Hama, Naoki, Wada, Hiroshi, Kawamoto, Koichi, Marubashi, Shigeru, Eguchi, Hidetoshi, Doki, Yuichiro, Mori, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452159/
https://ncbi.nlm.nih.gov/pubmed/25736055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12652
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