BRCA/Fanconi anemia pathway implicates chemoresistance to gemcitabine in biliary tract cancer

The BRCA/Fanconi anemia (FA) pathway plays a key role in the repair of DNA double strand breaks. We focused on this pathway to clarify chemoresistance mechanisms in biliary tract cancer (BTC). We also investigated changes in the CD24(+)/44(+) population that may be involved in chemoresistance, as th...

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Publicat a:Cancer Sci
Autors principals: Nakashima, Shinsuke, Kobayashi, Shogo, Nagano, Hiroaki, Tomokuni, Akira, Tomimaru, Yoshito, Asaoka, Tadafumi, Hama, Naoki, Wada, Hiroshi, Kawamoto, Koichi, Marubashi, Shigeru, Eguchi, Hidetoshi, Doki, Yuichiro, Mori, Masaki
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452159/
https://ncbi.nlm.nih.gov/pubmed/25736055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12652
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