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The HSP90 inhibitor ganetespib: A potential effective agent for Acute Myeloid Leukemia in combination with cytarabine

HSP90 is a multi-client chaperone involved in regulating a large array of cellular processes and is commonly overexpressed in many different cancer types including hematological malignancies. Inhibition of HSP90 holds promise for targeting multiple molecular abnormalities and is therefore an attract...

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Bibliografische gegevens
Gepubliceerd in:Leuk Res
Hoofdauteurs: Lazenby, M., Hills, R., Burnett, A.K., Zabkiewicz, J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Pergamon Press 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452084/
https://ncbi.nlm.nih.gov/pubmed/25882550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2015.03.016
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