Arginine-rhamnosylation as new strategy to activate translation elongation factor P

Ribosome stalling at polyproline stretches is common and fundamental. In bacteria, translation elongation factor P (EF-P) rescues such stalled ribosomes, but only when it is post-translationally activated. In Escherichia coli, activation of EF-P is achieved by (R)-β-lysinylation and hydroxylation of...

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Bibliografske podrobnosti
izdano v:Nat Chem Biol
Main Authors: Lassak, Jürgen, Keilhauer, Eva C, Fürst, Maximilian, Wuichet, Kristin, Gödeke, Julia, Starosta, Agata L, Chen, Jhong-Min, Søgaard-Andersen, Lotte, Rohr, Jürgen, Wilson, Daniel N, Häussler, Susanne, Mann, Matthias, Jung, Kirsten
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451828/
https://ncbi.nlm.nih.gov/pubmed/25686373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1751
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