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Synthesis of rhamnosylated arginine glycopeptides and determination of the glycosidic linkage in bacterial elongation factor P

A new class of N-linked protein glycosylation – arginine rhamnosylation – has recently been discovered as a critical modification for the function of bacterial elongation factor P (EF-P). Herein, we describe the synthesis of suitably protected α- and β-rhamnosylated arginine amino acid “cassettes” t...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Wang, Siyao, Corcilius, Leo, Sharp, Phillip P., Rajkovic, Andrei, Ibba, Michael, Parker, Benjamin L., Payne, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363394/
https://ncbi.nlm.nih.gov/pubmed/28451332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03847f
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