Diaphragm Muscle Fiber Weakness and Ubiquitin–Proteasome Activation in Critically Ill Patients

Rationale: The clinical significance of diaphragm weakness in critically ill patients is evident: it prolongs ventilator dependency, and increases morbidity and duration of hospital stay. To date, the nature of diaphragm weakness and its underlying pathophysiologic mechanisms are poorly understood....

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Bibliografski detalji
Izdano u:Am J Respir Crit Care Med
Glavni autori: Hooijman, Pleuni E., Beishuizen, Albertus, Witt, Christian C., de Waard, Monique C., Girbes, Armand R. J., Spoelstra-de Man, Angelique M. E., Niessen, Hans W. M., Manders, Emmy, van Hees, Hieronymus W. H., van den Brom, Charissa E., Silderhuis, Vera, Lawlor, Michael W., Labeit, Siegfried, Stienen, Ger J. M., Hartemink, Koen J., Paul, Marinus A., Heunks, Leo M. A., Ottenheijm, Coen A. C.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2015
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451621/
https://ncbi.nlm.nih.gov/pubmed/25760684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201412-2214OC
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